Chinese scientists make nano "Trojan hobrain twitchrse" to strangle tumorsBest Uk Music Festivals For 2012 Hiring a marquee sounds like an expensive proposition in general, but those of us who have never done it before will not have any idea how much it costs. The fact is prices range widely, depending on a number of variable factors, so it is impossible to generalise. The Cadieux Cafe played a role in the band"s early years as a part of the venue"s Mussel Beach festival wristbands in 2001. They have come a long way since and suffered some hardship and line-up changes along the way. In late 2001, bass player DeNardo experienced a serious stroke which left his right arm paralyzed. After a great deal of local outreach to fund his physical rehabilitation and an ingenious solution to keep him up front with the band, he now performs his bass-lines on a keyboard system. He"s back in fine form. If you"re worried about the facilities that you"re likely to find then make sure that you bring your own toilets. This may sound silly but it"s now perfectly possible thanks event wristbands to the latest range of folding camping toilets. Banquet Halls sure their main business are weddings and reunions but they offer ample space plus most have sport wristbands their own kitchens or catering services so Hosting a Dinner Theater would be perfect. Speaking of beer, drinks are not exactly dirt cheap at Off Broadway, but they are pretty reasonable for a respected St. Louis music venue. Stag and Pabst Blue Ribbon beers are $3 most nights, nicer beers might be a little more, and mixed drinks are usually closer to $5. Occasionally, they will offer a special, such as dollar PBRs, but it"s not routine. Confirmation dialogue box , which appears when you delete a file may seem unnecessary, especially if you have the Recycle Bin to recover them. To stop running, Right-click mice Trash and uncheck Display delete confirmation dialog options. For further information please visit us online. You can also read our other party fashion article for further help. Remember, we want you to look great and feel great about yourself.
BEIJING -- Chinese scientists have folded DNA molecules in an origami-like process to make a nano "Trojan horse", which is thinner than 1/4000 of a hair and can release "killers" to fight cancer tumors.
Cancer cells need a lot of nutrition to multiply, but they don"t produce nutrient substances, said lead researcher Nie Guangjun, of China"s National Center for Nanoscience and Technology (NCNST).
All the blood, oxygen and energy are conveyed to cancer cells through blood vessels, so many scientists are trying to create blocks on the blood vessels feeding tumors.
Through precision control, researcher Ding Baoquan folded a single-strand DNA of a phage (a type of virus) into a rectangular sheet. Then he put four "killers" -- molecules of thrombin (a clotting enzyme in blood plasma) -- on the sheet and rolled them up.
At the interface, "locks" made by fragments of nucleolin protein DNA were installed, forming a tube-shaped nano "Trojan horse" or nanorobot, which is 90 nanometers long and has a diameter of 19 nanometers.
After injection, the "Trojan horse" travels in blood vessels and only tumors have the "key" to open the "locks." Once unlocked, the killer thrombin molecules are released, attracting platelets and fibrinogen protein to form a large thrombus, or clot, in the blood vessel within hours to cut off the blood supply and "starve" the tumor to death, Nie said.
The nanorobot can be cleared out of the body after it has finished its task.
Researchers have conducted controlled experiments on more than 200 mice with melanoma, breast cancer, ovarian cancer and primary lung cancer, and found the nanorobots are effective in strangling the tumors, Nie said.
In one experiment on eight mice with melanoma, the tumors in three mice totally disappeared. The average survival life of the mice was prolonged from 20.5 days to 45 days. No metastasis was found, according to Nie.
The incidence of malignant tumors has been rising in China in recent years, becoming a major health threat. Interventional embolization therapy has become the first therapeutic choice for patients with advanced liver cancer. About 600,000 to 800,000 Chinese with liver cancer receive interventional therapy every year.
However, patients face anesthetic risks in this therapy and doctors face exposure to X-ray radiation, so a safer, more effective and convenient treatment is a priority, and nanotechnology has opened new opportunities, Nie said.
The research began five years ago, when NCNST researchers first looked at cutting off the tumor blood supply by using DNA-based nano carriers.
Shi Quanwei, another member of the research team, said laboratory verification of the nanorobot idea has been completed, but industrial production and application of the nanorobot is still a long way off.
"We hope to attract investment to improve the production technique and enlarge the manufacturing scale of the nanorobot, and conduct further research on its effect and safety before application for clinical trials," Shi said.
"We need to make breakthroughs on technical bottlenecks, and hope to transform the basic research into practical therapy to benefit patients with tumors."
The research was recently selected as one of 30 winning projects at a contest of innovative future technologies in Shenzhen, South China"s Guangdong province. The contest encouraged young Chinese scientists to conceive groundbreaking technologies and trigger innovation.personalized bracelets for girlfriendcustom circle braceletwristband onlinered white blue rubber braceletspersonalized bracelets for men